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Evidence-based substance profiles
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Register for free5-Amino-1-Methylquinolinium (5-Amino-1MQ)
Experimental NNMT inhibitor (IC50 ~1 µM) with preclinical evidence for fat reduction and metabolic improvement in mouse models; no completed human RCTs.
Acetyl-L-Carnitine (ALCAR)
Acetylated form of L-carnitine that crosses the blood-brain barrier; supports mitochondrial function, acetylcholine synthesis, and cognitive performance.
AD00464
AD00464 is a largely unknown compound with no published clinical studies, safety data, or demonstrated efficacy in humans.
Alpha-GPC (L-Alpha-Glycerylphosphorylcholine)
Alpha-GPC is a highly bioavailable choline compound that crosses the blood-brain barrier, promotes acetylcholine synthesis, and supports cognitive function and muscular performance.
Alpha-Lipoic Acid
Endogenous antioxidant with mitochondrial function; well-documented efficacy in diabetic neuropathy, evidence for metabolic and neuroprotective effects.
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